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View Full Version : Question about Remicade and Liver Enzymes


Momelie
12-18-2006, 09:38 AM
Can somebody tell me what the significance of elevated liver enzymes means when it shows up in routine bloodwork? Exactly how high is "elevated"? Would one expect them to be slightly elevated when on Remicade or is that a sign of trouble? Mine are about triple the normal level, after 6 months of Remicade. Would that be a reason to not take my next treatment on the 28th of this month?

I knew going in that I might have a problem, my liver seems to be my "trouble spot" when anything goes wrong. Eleven years ago I had systemic organ failure as a complication of pre-eclampsia, and ever since then, I've occasionally had mildly elevated levels. This time, my AST and ALT are significantly higher than those. However, Remicade seems to be the best option I've ever tried for my PA - it works, and up till now, no side effects.

Anybody know if this is a problem? Should I be investigating other PA treatment options? I have an appointment with my rheumy on January 5, but.... I usually have to do the homework and research on treatment myself, as he is extremely uncommunicative (might be a language barrier, or cultural - he's not rude or anything, just quiet).

Just wondering, since I have a Remicade infusion scheduled prior to my next doctor appointment, and just got the bloodwork results from my latest draws over the weekend. Should I worry?

ouchyk
12-18-2006, 10:32 AM
Hi,

Sorry to hear about the funky bloodwork...

These are definitely questions for your doctor to answer. Especially about the upcoming infusion.

Did he order and does he receive your blood results??

I would think if he saw your bloods being way off he would call, alert you, and make recommendations immediately.

Ahhhh geesh. Hope that you can touch base with him, I would insist on it.

Karen

Zwijndrecht
12-22-2006, 10:23 AM
Definitely check with doctor.
Are you taking methotrexate?
Are you taking much acetominophen? (tylenol)
Either of them are hell on your liver, especially if alcohol is mixed in, at low amounts.

Do not take chances .... it is not that you should immediately stop Remicade it is that you need to get a doctor to work with you on the importance of those level based on your past, present and drugs....

Good luck. Talk to docs.
Z