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From the Journal of Psoriasis and Psoriatic Arthritis®

Real-world evidence shows palmoplantar pustulosis has a greater disease burden than plaque psoriasis.

In recently published research in the Journal of Psoriasis and Psoriatic Arthritis®, investigators researched the clinical characteristics and patient-reported outcomes (PROs) of patients with palmoplantar pustulosis (PPP). This data set was compared to patients with plaque psoriasis and found that PPP was associated with worse PROs and a greater impact on quality of life.

To investigate these differences in patients with PPP versus plaque psoriasis, researchers utilized data from patients enrolled in CorEvitas Psoriasis Registry, a prospective, multicenter, observational, disease-based registry. Sixty-four patients with PPP and 4,894 patients with plaque psoriasis were identified and included in this analysis and they were of similar mean ages, education level, work status, and body mass index.

Findings showed that patients with PPP reported higher overall pain, a greater proportion of missed or affected work hours, greater impairment of work, and greater impairment of daily activity when compared to patients living with plaque psoriasis.

“The findings of this study highlight a clear need to develop detailed and effective approaches for the management of PPP so that the overall burden of this rare disease can be reduced and, ultimately, PROs and patient QoL can be improved,” the study authors concluded.

(Editors note: the Psoriasis Registry is a collaborative effort between the NPF and CorEvitas)

To read more about this research and other psoriasis and psoriatic arthritis research, please visit the Journal of Psoriasis and Psoriatic Arthritis®.

The journal currently is accepting articles of original research, review articles, case studies, commentary, and brief reports on all aspects of psoriatic disease including basic research, evaluation and diagnosis, heredity, pharmacotherapy, and symptom management.

Learn more about submitting your manuscript here.

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