Skyrizi (risankizumab-rzaa)

Skyrizi is a biologic that was approved for the treatment of moderate-to-severe plaque psoriasis and psoriatic arthritis.

What is Skyrizi?

Skyrizi (also known by its generic name risankizumab-rzaa) is a biologic medication that was approved by the FDA in April 2019 for the treatment of moderate-to-severe plaque psoriasis in adults. Skyrizi was approved by the FDA in January 2022 for the treatment of active psoriatic arthritis (PsA) in adults.

For both plaque psoriasis and PsA, Skyrizi is given by injection under the skin at week 0 (the first week of treatment) and week 4, and then every 12 weeks afterwards.

To learn more, please visit the Skyrizi website.

Skyrizi Fact Sheet

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Second SKYRIZI® Indication Approved

FDA approves SKYRIZI® for adults with active PsA

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Articles and Updates

Get the latest news on new treatment options from NPF.

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New Dosing Available for SKYRIZI®

SKYRIZI® (risankizumab-rzaa) is now available in the U.S. as a single dose injection for the treatment of adults with moderate-to-severe plaque psoriasis.

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Last updated on 3/24/25 by the National Psoriasis Foundation.