Xeljanz and Xeljanz XR (tofacitinib) are aimed at reducing psoriatic arthritis inflammation. Xeljanz targets a specific part of the immune system (Janus kinase) to reduce the overactive response associated with psoriatic disease. The oral treatment also aids in reducing joint tenderness and swelling.

What is Xeljanz?

How Is Xeljanz Used?

Xeljanz is taken by mouth twice daily as a pill. Xeljanz XR is an extended release formula of the same treatment and is taken by mouth once daily as a pill.

What Are the Risks?

Xeljanz/Xeljanz XR may raise your risk for:

  • High lipid levels
  • High liver enzymes
  • Low blood count
  • Lymphoma and other malignancies
  • Gastrointestinal perforations

Common Side Effects

In clinical trials, the most common side effects were headaches, diarrhea and upper respiratory infections.

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