Traditional Systemic Medications

Systemic medications are prescription drugs that work throughout the body. They are usually used for individuals with moderate to severe psoriasis and psoriatic arthritis. Systemic medications are also used in those who are not responsive or are unable to take topical medications or UV light therapy.

Systemic psoriasis drugs are taken by mouth in liquid or pill form or given by injection. Systemics have been used for more than 10 years.

Treatment Comparison Chart

Download the Systemic Treatments: Biologics and Oral Treatments Booklet (pdf) »

Learn more about traditional systemics

Do you have questions about traditional systemic medications?

NPF’s Patient Navigation Center is the world's first, personalized support center for psoriatic disease. Our Patient Navigators can teach you about the different types of systemics and help you understand their side effects.

For free and confidential assistance, contact our Patient Navigators »