Palmoplantar pustular psoriasis (PPPP), also known as palmoplantar pustulosis, is the most common form of pustular psoriasis and is localized on the palms, the soles of the feet, or both.
While GPP is known to spontaneously remit, PPPP is a chronic condition and can take months or years to get under control.
When PPPP flares, it causes discolored skin with large yellow or white pustules scattered throughout. The pustules can darken and turn brown as they dry. Affected skin can scale, crack, and fissure, and outbreaks can last for a considerable amount of time.
Although some people with PPPP also have plaque psoriasis (15.8%) it is less common.
Women develop PPPP at a significantly higher proportion than men (3.5 times) and the majority (79.8%) of people with PPPP are current or past smokers.
Pustular Psoriasis Resource Center
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