Psoriasis treatments

Finding the right psoriasis treatment — or combination of psoriasis treatments — can be hard. What works for one person may not work for you. It’s important to understand what’s new and what your options are when it comes to treatment. Keep working with your doctor to find the best treatment plan that reduces or eliminates your symptoms..

To learn more about treatments, contact NPF’s Patient Navigation Center. Our patient navigators provide free and confidential assistance to help you understand the latest treatments for psoriasis and psoriatic arthritis.


Biologic drugs, or biologics, are typically prescribed for moderate to severe psoriasis and psoriatic arthritis that has not responded to other treatments. Biologics are given by injection or intravenous (IV) infusion. Read about biologic treatments »


Systemic treatments are prescription drugs that are taken orally or by injection and work throughout the body. Systemics are typically prescribed for moderate to severe psoriasis and psoriatic arthritis. Read about systemic treatments »


Phototherapy, or light therapy, involves exposing the skin to ultraviolet light on a regular basis under medical supervision. Phototherapy is administered in a doctor's office, clinic or at home with a phototherapy unit. Read about phototherapy »

New oral treatments

New oral treatments improve symptoms of psoriatic disease by inhibiting specific molecules associated with inflammation. Unlike biologics, which are derived from living sources and must be administered via injection or infusion, these treatments can be effectively delivered as oral tablets. Read about new oral treatments »


Topical treatments are applied to the skin and are often the first treatment recommended to a newly diagnosed person. Topicals can be purchased over the counter or by prescription. Read about topical treatments »

Complementary and alternative medicine

Complementary and alternative medicine (CAM) is a group of diverse medical and health care systems, practices and products that are not presently considered to be part of conventional, or Western, medicine. More about CAM »


Find the right treatment for you

Learn your treatment options and how they differ with NPF's treatment comparison fact sheet

Test your treatment IQ

How much do you know about your psoriatic disease treatment options? Put your knowledge to the test with our treatment quiz and let NPF help you fill in some of the gaps.


Last updated  by the National Psoriasis Foundation.