Purpose
Milestones to a Cure challenges researchers to think boldly and creatively about what will need to be known — mechanistically, clinically, and translationally — to eventually declare psoriatic disease cured. By supporting especially innovative, high impact approaches, Milestones to a Cure aims to highlight critical research questions and accelerate progress toward the discoveries that will enable a cure for psoriatic disease.
Areas of interest include, but are not limited to:
- Novel approaches to achieving complete remission and preventing relapse
- Mechanisms of immune memory and durable remission
- Identification of markers of ongoing disease activity
- Understanding the relationship between psoriatic disease and associated comorbidities
- Personalized approaches to disease control and restoration of immune homeostasis
Applicants
The applicant must be an independent investigator and actively responsible for the conduct of the proposed research. The applicant must be eligible to apply as a principal investigator for research grants under the policies of the applicant’s host institution.
Budget and Project Period
Applicants may request up to USD$250,000 per year. Up to 10% indirect costs may be included, for a maximum total budget of $500,000. The project period for this Request for Proposals is two (2) years, from May 1, 2026 – April 30, 2028.
Key dates
- Letter of Intent deadline August 31, 2026
- LOI Notification Sept 21, 2026
- RFP submission deadline: December 1, 2026
- Award notification: March 1, 2027
- Award start: May 1, 2027
Application
Letters of Intent are due August 31. Award notifications are anticipated by March 1, 2027.