A new psoriasis drug that’s delivered dramatic skin improvement has been approved by the Food and Drug Administration (FDA).
Cosentyx (secukinumab), an injectable biologic drug manufactured by Novartis, has won approval for the treatment of chronic plaque psoriasis. In clinical trials, more than half of patients taking Cosentyx experienced clear or almost clear skin, while the majority experienced significant improvement.
In one trial, more than a quarter of patients achieved a 100 percent improvement in their skin, as measured by the Psoriasis Area and Severity Index. This measurement, also known as PASI 100, means that the patient had no psoriasis anywhere on their body. Almost 82 percent of patients in the same trial achieved 75 percent improvement, or PASI 75.
Other data on the drug indicate that the level of improvement delivered by Cosentyx can be long-lasting.
Results from another Phase III trial suggest that Cosentyx is also an effective treatment for psoriatic arthritis. Novartis plans to apply for FDA approval for Cosentyx as a psoriatic arthritis drug later this year.
Cosentyx targets interleukin-17A (IL-17A), which is a protein, or cytokine, that triggers inflammation. IL-17 is a key cytokine in psoriasis, and, according to the researchers, may even be a “master cytokine,” responsible for a series of inflammatory reactions.
Driving Discovery, Creating Community
This year, we’re celebrating 50 years of driving efforts to cure psoriatic disease and improve the lives of those affected. See how far we’ve come with this timeline of NPF’s history. But there’s still plenty to do, and we can’t do it without you! Learn how you can help our advocacy team shape the laws and policies that affect people with psoriasis and psoriatic arthritis – in your state and across the country. Help us raise funding to promote research into better treatments and a cure by joining Team NPF, where you can walk, run, cycle, play bingo or even create your own DIY event. Contact our Patient Navigation Center for free, personalized support for living a healthier life with psoriatic disease. And keep the National Psoriasis Foundation going strong by making a donation today! Together, we will find a cure.