Treatments in Phase 2 Trials

Biologics

Name: ABY-035/AFO2
Indication: Psoriasis

  • Affibody
  • IL-17A inhibitor


Name: M1095/ALX-0761
Indication: Psoriasis

  • Merck
  • IL-17A and IL-17F inhibitor


Name: Namilumab (MT203)
Indication: Psoriasis

  • Takeda
  • Granulocyte macrophage colony stimulating factor antagonist


Name: SHR-1314
Indication: Psoriasis

  • Jiangsu HengRui Medicine Co., Ltd.
  • IL-17A Antagonist


Name: Tildrakizumab (MK-3222/SCH 900222/SUNPG1623)
Indication: PsA

  • Merck and Sun Pharma
  • IL-23 inhibitor
  • Approved to treat psoriasis

Oral Treatments

Name: Apo805K1
Indication: Psoriasis

  • ApoPharma

Name: BI 730357
Indication: Psoriasis

  • Boehringer Ingelheim
  • Nuclear Receptor Antagonist

Name: FP187
Indication: Psoriasis

  • Forward-Pharma
  • Fumaric acid

Name: JTE-451
Indication: Psoriasis

  • Akros Pharma Inc.
  • RORγ Antagonist

Name: KD025 (SLx-2119)
Indication: Psoriasis

  • Kadmon Corporation
  • ROCK2 inhibitor

Name: PF-06826647
Indication: Psoriasis

  • Pfizer
  • TYK2 Inhibitor

Name: Prurisol
Indication: Psoriasis

  • Cellceutix Corporation
  • IL-20 and PRINS inhibitor

Name: XP23829
Indication: Psoriasis

  • Dr. Reddy’s Laboratories and XenoPort
  • Fumaric acid

Name: ZPL-389
Indication: Psoriasis

  • Ziarco Pharma Ltd.
  • Histamine H4 receptor antagonist

Topicals

Name: ARQ-151
Indication: Psoriasis

  • Arcutis
  • PDE4 Enzyme Inhibitor

Name: EISO (SAN021)
Indication: Psoriasis

  • Santalis Pharmaceutical, Inc.
  • PDE4 blocker

Name: Eucrisa (crisaborole/AN2728)
Indication: Psoriasis

  • Pfizer
  • Phosphodiesterase-4 inhibitor
  • Approved for atopic dermatitis

Name: LAS41004
Indication: Psoriasis

  • Almirall/Aqua
  • Bexarotene/betamethasone dipropionate

Name: PF-06700841
Indication: Psoriasis and PsA

  • Pfizer
  • JAK1 and TYK2 inhibitor

Name: PH-10
Indication: Psoriasis

  • Provectus Biopharmaceuticals
  • Rose Bengal

Name: SNA-120 (CT 327/pegcantratinib)
Indication: Psoriasis

  • Sienna Biopharmaceuticals/Creabilis SA
  • TrkA kinase blocker

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